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Published by: Massachusetts Institute of Technology | Language: English
Published by: Massachusetts Institute of Technology | Language: English
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The course applies molecular biology and reverse genetics approaches to the study of apoptosis, or programmed cell death (PCD), in Drosophila cells. RNA interference (RNAi), or double stranded RNA-mediated gene silencing, will be used to inhibit expression of candidate apoptosis-related genes in cultured Drosophila cells. Teams of 2 or 3 st
Author(s):
Tag(s):
- biology
- rnai
- rna interference
- programmed cell death
- drosophilia
- pcd
- mrna
- lab notebook
- scientific writing
- rt-pcr
- s2 rna
- s2
- cell culture
- genetic transcription
- dsrna
- bioinformatics
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Published by: Massachusetts Institute of Technology | Language: English
Published by: Massachusetts Institute of Technology | Language: English
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This course will start with a survey of basic oxygen radical biochemistry followed by a discussion of the mechanisms of action of cellular as well as dietary antioxidants. After considering the normal physiological roles of oxidants, we will examine the effects of elevated ROS and a failure of cellular redox capacity on the rate of organism
Author(s):
Tag(s):
- biology
- reactive oxygen species
- oxygen
- ros
- energy
- mitochondria
- cell signaling
- anti-pathogen
- oxidative damage
- oncogene
- antioxidant
- insulin resistance
- diabetes
- stem cell
- neurodegenerative
- ischemic
- atp
- pathways
- nadph
- nox
- psd
- programmed cell death
- apoptosis
- hsc
- hematopoietic
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Published by: Massachusetts Institute of Technology | Language: English
Published by: Massachusetts Institute of Technology | Language: English
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Cancer is a leading cause of death worldwide. Cancer involves uncontrolled cell growth, resistance to cell death, failure to differentiate into a particular cell type, and increased cellular motility. A family of gate-keeper genes, known as tumor suppressor genes, plays important roles in preventing the initiation and progression of cancer.
Author(s):
Tag(s):
- biology
- tumor suppressor gene
- p53
- p53 protein
- cancer
- cell-growth signals
- cell cycle regulation
- dna damage
- dna repair
- programmed cell death
- apoptosis
- genome integrity
- oncogenes
- p53 mutations
- mouse cancer models
- mdm2
- microrna
File: 7-343-fall-2007.zip
This OER is part of OCW: The Radical Consequences of Respiration: Reactive Oxygen Species in Aging and Disease
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Inherited Tag(s):
- biology
- reactive oxygen species
- oxygen
- ros
- energy
- mitochondria
- cell signaling
- anti-pathogen
- oxidative damage
- oncogene
- antioxidant
- insulin resistance
- diabetes
- stem cell
- neurodegenerative
- ischemic
- atp
- pathways
- nadph
- nox
- psd
- programmed cell death
- apoptosis
- hsc
- hematopoietic
File: 7-16-spring-2005.zip
This OER is part of OCW: Experimental Molecular Biology: Biotechnology II
Published under: /Download Course Materials
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Inherited Tag(s):
- biology
- rnai
- rna interference
- programmed cell death
- drosophilia
- pcd
- mrna
- lab notebook
- scientific writing
- rt-pcr
- s2 rna
- s2
- cell culture
- genetic transcription
- dsrna
- bioinformatics
File: 7-344-fall-2010.zip
This OER is part of OCW: Tumor Suppressor Gene p53: How the Guardian of our Genome Prevents Cancer
Published under: /Download Course Materials
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Inherited Tag(s):
- biology
- tumor suppressor gene
- p53
- p53 protein
- cancer
- cell-growth signals
- cell cycle regulation
- dna damage
- dna repair
- programmed cell death
- apoptosis
- genome integrity
- oncogenes
- p53 mutations
- mouse cancer models
- mdm2
- microrna
File: minireview.pdf
This OER is part of OCW: Experimental Molecular Biology: Biotechnology II
Published under: /Assignments
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OCW Authors:
Inherited Tag(s):
- biology
- rnai
- rna interference
- programmed cell death
- drosophilia
- pcd
- mrna
- lab notebook
- scientific writing
- rt-pcr
- s2 rna
- s2
- cell culture
- genetic transcription
- dsrna
- bioinformatics
File: stafford_minirev.pdf
This OER is part of OCW: Experimental Molecular Biology: Biotechnology II
Published under: /Assignments
Share in:
OCW Authors:
Inherited Tag(s):
- biology
- rnai
- rna interference
- programmed cell death
- drosophilia
- pcd
- mrna
- lab notebook
- scientific writing
- rt-pcr
- s2 rna
- s2
- cell culture
- genetic transcription
- dsrna
- bioinformatics
File: finalpaper.pdf
This OER is part of OCW: Experimental Molecular Biology: Biotechnology II
Published under: /Assignments
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OCW Authors:
Inherited Tag(s):
- biology
- rnai
- rna interference
- programmed cell death
- drosophilia
- pcd
- mrna
- lab notebook
- scientific writing
- rt-pcr
- s2 rna
- s2
- cell culture
- genetic transcription
- dsrna
- bioinformatics
File: stafford_prop.pdf
This OER is part of OCW: Experimental Molecular Biology: Biotechnology II
Published under: /Assignments
Share in:
OCW Authors:
Inherited Tag(s):
- biology
- rnai
- rna interference
- programmed cell death
- drosophilia
- pcd
- mrna
- lab notebook
- scientific writing
- rt-pcr
- s2 rna
- s2
- cell culture
- genetic transcription
- dsrna
- bioinformatics
File: proposal.pdf
This OER is part of OCW: Experimental Molecular Biology: Biotechnology II
Published under: /Assignments
Share in:
OCW Authors:
Inherited Tag(s):
- biology
- rnai
- rna interference
- programmed cell death
- drosophilia
- pcd
- mrna
- lab notebook
- scientific writing
- rt-pcr
- s2 rna
- s2
- cell culture
- genetic transcription
- dsrna
- bioinformatics
File: stafford_final.pdf
This OER is part of OCW: Experimental Molecular Biology: Biotechnology II
Published under: /Assignments
Share in:
OCW Authors:
Inherited Tag(s):
- biology
- rnai
- rna interference
- programmed cell death
- drosophilia
- pcd
- mrna
- lab notebook
- scientific writing
- rt-pcr
- s2 rna
- s2
- cell culture
- genetic transcription
- dsrna
- bioinformatics
File: paper1.pdf
This OER is part of OCW: The Radical Consequences of Respiration: Reactive Oxygen Species in Aging and Disease
Published under: /Assignments
Share in:
OCW Authors:
Inherited Tag(s):
- biology
- reactive oxygen species
- oxygen
- ros
- energy
- mitochondria
- cell signaling
- anti-pathogen
- oxidative damage
- oncogene
- antioxidant
- insulin resistance
- diabetes
- stem cell
- neurodegenerative
- ischemic
- atp
- pathways
- nadph
- nox
- psd
- programmed cell death
- apoptosis
- hsc
- hematopoietic
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Pages: 2
This OER is part of OCW: The Radical Consequences of Respiration: Reactive Oxygen Species in Aging and Disease
Published under: /Readings
This OER is part of OCW: The Radical Consequences of Respiration: Reactive Oxygen Species in Aging and Disease
Published under: /Readings
Share in:
OCW Authors:
Inherited Tag(s):
- biology
- reactive oxygen species
- oxygen
- ros
- energy
- mitochondria
- cell signaling
- anti-pathogen
- oxidative damage
- oncogene
- antioxidant
- insulin resistance
- diabetes
- stem cell
- neurodegenerative
- ischemic
- atp
- pathways
- nadph
- nox
- psd
- programmed cell death
- apoptosis
- hsc
- hematopoietic
More OERs like this |
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Pages: 0
This OER is part of OCW: The Radical Consequences of Respiration: Reactive Oxygen Species in Aging and Disease
Published under: /Readings
This OER is part of OCW: The Radical Consequences of Respiration: Reactive Oxygen Species in Aging and Disease
Published under: /Readings
Share in:
OCW Authors:
Inherited Tag(s):
- biology
- reactive oxygen species
- oxygen
- ros
- energy
- mitochondria
- cell signaling
- anti-pathogen
- oxidative damage
- oncogene
- antioxidant
- insulin resistance
- diabetes
- stem cell
- neurodegenerative
- ischemic
- atp
- pathways
- nadph
- nox
- psd
- programmed cell death
- apoptosis
- hsc
- hematopoietic
More OERs like this |
|
Pages: 3
This OER is part of OCW: The Radical Consequences of Respiration: Reactive Oxygen Species in Aging and Disease
Published under: /Readings
This OER is part of OCW: The Radical Consequences of Respiration: Reactive Oxygen Species in Aging and Disease
Published under: /Readings
Share in:
OCW Authors:
Inherited Tag(s):
- biology
- reactive oxygen species
- oxygen
- ros
- energy
- mitochondria
- cell signaling
- anti-pathogen
- oxidative damage
- oncogene
- antioxidant
- insulin resistance
- diabetes
- stem cell
- neurodegenerative
- ischemic
- atp
- pathways
- nadph
- nox
- psd
- programmed cell death
- apoptosis
- hsc
- hematopoietic
48 results found.
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