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File: 7-342-spring-2008.zip
This OER is part of OCW: Developmental and Molecular Biology of Regeneration
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Inherited Tag(s):
- biology
- regeneration
- blastema
- embryo
- progenitor
- stem cells
- differentiation
- dedifferentiation
- hydra
- morphallaxis
- limb
- organ
- zebrafish
- homeostasis
- self-renewal
- regenerative medicine
- differentitate
- regulate
- salamander
- catenin
- newt
- liver
- pluriptent
- fibroblast
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Description:How does a regenerating animal "know" what's missing? How are stem cells or differentiated cells used to create new tissues during regeneration? In this class we will take a comparative approach to explore this fascinating problem by critically examining classic and modern scientific literature about the developmental and molecular biology
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Description:In this course, we will address how transcriptional regulators both prohibit and drive differentiation during the course of development. How does a stem cell know when to remain a stem cell and when to become a specific cell type? Are there global differences in the way the genome is read in multipotent and terminally differentiated cells?
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Description:In this course, we will address how transcriptional regulators both prohibit and drive differentiation during the course of development. How does a stem cell know when to remain a stem cell and when to become a specific cell type? Are there global differences in the way the genome is read in multipotent and terminally differentiated cells?
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