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Published by: Massachusetts Institute of Technology | Language: English
Published by: Massachusetts Institute of Technology | Language: English
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In this course, we will address how transcriptional regulators both prohibit and drive differentiation during the course of development. How does a stem cell know when to remain a stem cell and when to become a specific cell type? Are there global differences in the way the genome is read in multipotent and terminally differentiated cells?
Author(s):
Tag(s):
- biology
- blueprint of life
- transcription
- stem cells
- differentiation
- human tissues
- tissue regeneration
- human disease
- rna and protein expression patterns
- transcriptional regulation
- specialized gene expression programs
- genome
- multipotent
- terminally differentiated
- pluripotency
- master regulators
- chromatin regulators
- developmental defects
More OCW like this |
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Published by: Massachusetts Institute of Technology | Language: English
Published by: Massachusetts Institute of Technology | Language: English
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During development, the genetic content of each cell remains, with a few exceptions, identical to that of the zygote. Most differentiated cells therefore retain all of the genetic information necessary to generate an entire organism. It was through pioneering technology of somatic cell nuclear transfer (SCNT) that this concept was experimen
Author(s):
Tag(s):
- biology
- embryonic stem cells
- stem cells
- cells
- genetics
- genome
- dolly
- clone
- regenerative therapy
- somatic
- scnt
- pluripotent
- scientific literature
- nuclear
- embryonic
- adult
- epigenetics
- methylation
- dna
- histone
- biomedical
- differentiation
- epigenome
- nuclear transfer
- customized
- zygote
- rna
- cancer
- medicine
File: 7-342-fall-2006.zip
This OER is part of OCW: Reading the Blueprint of Life: Transcription, Stem Cells and Differentiation
Published under: /Download Course Materials
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Inherited Tag(s):
- biology
- blueprint of life
- transcription
- stem cells
- differentiation
- human tissues
- tissue regeneration
- human disease
- rna and protein expression patterns
- transcriptional regulation
- specialized gene expression programs
- genome
- multipotent
- terminally differentiated
- pluripotency
- master regulators
- chromatin regulators
- developmental defects
File: 7-344-fall-2007.zip
This OER is part of OCW: The Fountain of Life: From Dolly to Customized Embryonic Stem Cells
Published under: /Download Course Materials
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Used by:
Inherited Tag(s):
- biology
- embryonic stem cells
- stem cells
- cells
- genetics
- genome
- dolly
- clone
- regenerative therapy
- somatic
- scnt
- pluripotent
- scientific literature
- nuclear
- embryonic
- adult
- epigenetics
- methylation
- dna
- histone
- biomedical
- differentiation
- epigenome
- nuclear transfer
- customized
- zygote
- rna
- cancer
- medicine
File: proposal_guide.pdf
This OER is part of OCW: Reading the Blueprint of Life: Transcription, Stem Cells and Differentiation
Published under: /Assignments
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OCW Authors:
Inherited Tag(s):
- biology
- blueprint of life
- transcription
- stem cells
- differentiation
- human tissues
- tissue regeneration
- human disease
- rna and protein expression patterns
- transcriptional regulation
- specialized gene expression programs
- genome
- multipotent
- terminally differentiated
- pluripotency
- master regulators
- chromatin regulators
- developmental defects
File: 1805.pdf
This OER is part of OCW: Reading the Blueprint of Life: Transcription, Stem Cells and Differentiation
Published under: /Readings
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OCW Authors:
Inherited Tag(s):
- biology
- blueprint of life
- transcription
- stem cells
- differentiation
- human tissues
- tissue regeneration
- human disease
- rna and protein expression patterns
- transcriptional regulation
- specialized gene expression programs
- genome
- multipotent
- terminally differentiated
- pluripotency
- master regulators
- chromatin regulators
- developmental defects
File: 6425.pdf
This OER is part of OCW: Reading the Blueprint of Life: Transcription, Stem Cells and Differentiation
Published under: /Readings
Share in:
OCW Authors:
Inherited Tag(s):
- biology
- blueprint of life
- transcription
- stem cells
- differentiation
- human tissues
- tissue regeneration
- human disease
- rna and protein expression patterns
- transcriptional regulation
- specialized gene expression programs
- genome
- multipotent
- terminally differentiated
- pluripotency
- master regulators
- chromatin regulators
- developmental defects
File: 1123.pdf
This OER is part of OCW: Reading the Blueprint of Life: Transcription, Stem Cells and Differentiation
Published under: /Readings
Share in:
OCW Authors:
Inherited Tag(s):
- biology
- blueprint of life
- transcription
- stem cells
- differentiation
- human tissues
- tissue regeneration
- human disease
- rna and protein expression patterns
- transcriptional regulation
- specialized gene expression programs
- genome
- multipotent
- terminally differentiated
- pluripotency
- master regulators
- chromatin regulators
- developmental defects
File: 11241.pdf
This OER is part of OCW: Reading the Blueprint of Life: Transcription, Stem Cells and Differentiation
Published under: /Readings
Share in:
OCW Authors:
Inherited Tag(s):
- biology
- blueprint of life
- transcription
- stem cells
- differentiation
- human tissues
- tissue regeneration
- human disease
- rna and protein expression patterns
- transcriptional regulation
- specialized gene expression programs
- genome
- multipotent
- terminally differentiated
- pluripotency
- master regulators
- chromatin regulators
- developmental defects
File: 2315.pdf
This OER is part of OCW: Reading the Blueprint of Life: Transcription, Stem Cells and Differentiation
Published under: /Readings
Share in:
OCW Authors:
Inherited Tag(s):
- biology
- blueprint of life
- transcription
- stem cells
- differentiation
- human tissues
- tissue regeneration
- human disease
- rna and protein expression patterns
- transcriptional regulation
- specialized gene expression programs
- genome
- multipotent
- terminally differentiated
- pluripotency
- master regulators
- chromatin regulators
- developmental defects
File: 5434.pdf
This OER is part of OCW: Reading the Blueprint of Life: Transcription, Stem Cells and Differentiation
Published under: /Readings
Share in:
OCW Authors:
Inherited Tag(s):
- biology
- blueprint of life
- transcription
- stem cells
- differentiation
- human tissues
- tissue regeneration
- human disease
- rna and protein expression patterns
- transcriptional regulation
- specialized gene expression programs
- genome
- multipotent
- terminally differentiated
- pluripotency
- master regulators
- chromatin regulators
- developmental defects
File: 2685.pdf
This OER is part of OCW: Reading the Blueprint of Life: Transcription, Stem Cells and Differentiation
Published under: /Readings
Share in:
OCW Authors:
Inherited Tag(s):
- biology
- blueprint of life
- transcription
- stem cells
- differentiation
- human tissues
- tissue regeneration
- human disease
- rna and protein expression patterns
- transcriptional regulation
- specialized gene expression programs
- genome
- multipotent
- terminally differentiated
- pluripotency
- master regulators
- chromatin regulators
- developmental defects
File: 553.pdf
This OER is part of OCW: Reading the Blueprint of Life: Transcription, Stem Cells and Differentiation
Published under: /Readings
Share in:
OCW Authors:
Inherited Tag(s):
- biology
- blueprint of life
- transcription
- stem cells
- differentiation
- human tissues
- tissue regeneration
- human disease
- rna and protein expression patterns
- transcriptional regulation
- specialized gene expression programs
- genome
- multipotent
- terminally differentiated
- pluripotency
- master regulators
- chromatin regulators
- developmental defects
File: 1855.pdf
This OER is part of OCW: Reading the Blueprint of Life: Transcription, Stem Cells and Differentiation
Published under: /Readings
Share in:
OCW Authors:
Inherited Tag(s):
- biology
- blueprint of life
- transcription
- stem cells
- differentiation
- human tissues
- tissue regeneration
- human disease
- rna and protein expression patterns
- transcriptional regulation
- specialized gene expression programs
- genome
- multipotent
- terminally differentiated
- pluripotency
- master regulators
- chromatin regulators
- developmental defects
File: stemcell_010907.pdf
This OER is part of OCW: The Fountain of Life: From Dolly to Customized Embryonic Stem Cells
Published under: /Readings
Share in:
OCW Authors:
Inherited Tag(s):
- biology
- embryonic stem cells
- stem cells
- cells
- genetics
- genome
- dolly
- clone
- regenerative therapy
- somatic
- scnt
- pluripotent
- scientific literature
- nuclear
- embryonic
- adult
- epigenetics
- methylation
- dna
- histone
- biomedical
- differentiation
- epigenome
- nuclear transfer
- customized
- zygote
- rna
- cancer
- medicine
15 results found.
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